- What part of the body does porphyria affect?
- Where does porphyria come from?
- What medications should be avoided with porphyria?
- Where is porphyria most common?
- When should you suspect porphyria?
- Does porphyria make you crave blood?
- Is Porphyria a disability?
- Is porphyria more common in males or females?
- What is a porphyria attack?
- What is the life expectancy of someone with porphyria?
- Is Porphyria a mental illness?
- What foods should be avoided with porphyria?
- What triggers porphyria?
- What does a porphyria attack feel like?
- How do you stop a porphyria attack?
What part of the body does porphyria affect?
There are two general categories of porphyria: acute, which mainly affects the nervous system, and cutaneous, which mainly affects the skin.
Some types of porphyria have both nervous system symptoms and skin symptoms.
Signs and symptoms of porphyria vary, depending on the specific type and severity..
Where does porphyria come from?
Porphyria is named from the ancient Greek word porphura, meaning purple. The Greeks borrowed the term from the Phoenicians, who extracted a purple pigment from purpura mollusks to dye the garments of their royal family.
What medications should be avoided with porphyria?
These include, but are not limited to, certain anesthetics, antihistamines, antiepileptics, antihyperglycemics (like those used to treat diabetes), some antibiotics, and some heart medicines. Sex hormone treatments for women, such as implanted or injected contraceptives, can also cause acute porphyria attacks.
Where is porphyria most common?
Acute intermittent porphyria is the most common form of acute porphyria in most countries. It may occur more frequently in northern European countries, such as Sweden, and in the United Kingdom. Another form of the disorder, hereditary coproporphyria, has been reported mostly in Europe and North America.
When should you suspect porphyria?
The risk of hepatocellular carcinoma is increased in the acute porphyrias (6,7). Therefore, it is currently recommended that patients undergo screening by liver imaging for early detection at least yearly after age 50, especially if porphobilinogen (PBG) remains elevated.
Does porphyria make you crave blood?
People with porphyria experience the desire to drink human blood to alleviate their symptoms (the genetic disease causes abnormalities in a person’s hemoglobin, a protein found in red blood cells), declared biochemist David Dolphin.
Is Porphyria a disability?
People who have been diagnosed with Porphyria can experience a range of uncomfortable or even debilitating symptoms, and in some cases, getting the Social Security disability benefits that they need can be the best opportunity to continue to take care of themselves when they can’t go to work.
Is porphyria more common in males or females?
Clinical manifestations are more common in women than men. VP can cause acute attacks identical to those in AIP, with abdominal pain, vomiting, constipation, hypertension, tachycardia, and neuromuscular weakness that can progress to quadriplegia and respiratory weakness (Chemmanur and Bonkovsky, 2004).
What is a porphyria attack?
Acute intermittent porphyria, which causes abdominal pain and neurologic symptoms, is the most common acute porphyria. Many people never experience symptoms. Symptoms may include vomiting, abdominal or back pain, weakness in arms or legs, and mental symptoms.
What is the life expectancy of someone with porphyria?
Patients with porphyria generally have a normal life expectancy. However, those with acute hepatic porphyria are at increased risk of developing high blood pressure, chronic kidney disease, and hepatocellular carcinoma (liver cancer), which may reduce their lifespan.
Is Porphyria a mental illness?
Acute intermittent porphyria mimics a variety of commonly occurring disorders and thus poses a diagnostic quagmire. Psychiatric manifestations include hysteria, anxiety, depression, phobias, psychosis, organic disorders, agitation, delirium, and altered consciousness ranging from somnolence to coma.
What foods should be avoided with porphyria?
The main dietary advice for persons with Porphyria Cutanea Tarda is to avoid all alcohol in any form. In addition, adherence to a low iron diet with avoidance of any medicinal iron and with ingestion of limited amounts of liver or red meat, is recommended, at least until remission of active PCT has been achieved.
What triggers porphyria?
Porphyria can be triggered by drugs (barbiturates, tranquilizers, birth control pills, sedatives), chemicals, fasting, smoking, drinking alcohol, infections, emotional and physical stress, menstrual hormones, and exposure to the sun. Attacks of porphyria can develop over hours or days and last for days or weeks.
What does a porphyria attack feel like?
The most commonly reported debilitating symptoms are diffuse severe pain affecting the abdomen, back, or limbs; other common attack signs and symptoms include nausea and vomiting, constipation, hypertension, motor weakness, insomnia, or anxiety [1–3, 5].
How do you stop a porphyria attack?
Avoiding triggers may include:Not using medications known to trigger acute attacks. … Not using alcohol or recreational drugs.Avoiding fasting and dieting that involves severe calorie restriction.Not smoking.Taking certain hormones to prevent premenstrual attacks.Minimizing sun exposure.More items…•